Cigarette smoking kills almost half a million Americans every year. It killed Deanna Sampson’s father, sickened her, and nearly claimed her husband, too. It gave Matt Culley oral cancer at just 30 years old, and it led a 37-year-old Ryan Bliss to develop “the cardiovascular system of an 80-year-old.” It is still the leading cause of preventable death in the United States, even decades after Americans were first made aware of the myriad health risks associated with smoking.